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MannaCLEANSE™ caplets |
Ingredients
Aloe vera (inner leaf gel powder)Aloe vera (inner leaf gel powder)
Aloe vera gel. For centuries, the aloe vera plant, Aloe barbadensis, has been used by cultures for its beneficial effects on human health (1). Today aloe vera gel continues to be used in supplements, foods, beverages, and cosmetics. Aloe leaves consist of two major parts, the outer leaf epidermis and the inner leaf gel, which are very different in their chemical composition and properties. Aloe gel is obtained from the inner portion of the leaves. Much of the health benefits observed by the use of aloe vera gel may be attributed to its high molecular weight polysaccharides. Before a process was developed to stabilize aloe vera gel or extracts, fresh preparations were regarded as being required for any therapeutic efficacy (2). It has now been shown that careful drying of aloe vera gel can retain the polysaccharide content important for producing many of its health benefits (3).
There are very few studies exploring what happens to aloe vera gel once ingested. It has been demonstrated that the human gut bacteria can digest polysaccharides from aloe vera (4). Aloe has a long history of safe use, dating back thousands of years.This ingredient can be found in the following products:
References
• Advanced Ambrotose® capsules
• Advanced Ambrotose® powder
• AmbroStart® drink mix
• Ambrotose AO® capsules
• Ambrotose® Complex capsules
• CardioBALANCE® capsules
• Catalyst™ caplets
• EM•PACT®
• GlycoBears® tablets
• MannaBears™ supplement
• Manna-C™ capsules
• MannaCLEANSE™ caplets
• Optimal Support Packets
• Phyt-Aloe® capsules or powder
• PhytoBurst® Nutritional Chews
• PhytoMatrix® caplets
• PLUS™ caplets
• SPORT™ capsules
References
1. The Merck Index. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
2. Gjerstad G, Riner TD. Am J Pharm Sci Support Public Health 1968;140:58-64.
3. Ni Y, Turner D, Yates KM, Tizard I. Isolation and characterization of structural components of Aloe vera L. leaf pulp. Int J Immunopharmacol. 2004;4:1745-55.
4. Sinnott RA, Ramberg J, Kirchner JM et al. Utilization of arabinogalactan, aloe vera gel polysaccharides, and a mixed saccharide dietary supplement by human colonic bacteria in vitro. Int J Probiotics Prebiotics 2007;2:97-104.
Last updated March, 2009
Print This Ingredient- Amylase
Amylase
Amylase is an enzyme produced by the salivary glands and the pancreas that can break down starch, glycogen and related polysaccharides into simple sugars (1). Amylase derived from widely utilized fungi and bacteria, such as Aspergillus niger and Bacillus subtilis, is approved for use as a food enzyme by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• GI-PRO® capsules
• GI-ZYME® capsules
• MannaCLEANSE™ caplets
References
1. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.
Last updated March, 2009
Print This Ingredient- Arabinogalactan (from Larix spp. wood)
Arabinogalactan (from Larix spp. wood)
Arabinogalactans are a class of long, densely branched high-molecular weight polysaccharides extracted for commercial uses from the bark of the Eastern and Western Larch trees, Larix larcinia and Larix occidentalis. Larch arabinogalactans are considered a good source of soluble dietary fiber. Arabinogalactans are common in many food plants, including corn, carrots, tomatoes, pears, wheat and red wine (1).
The amount of arabinogalactan absorbed through the intestine after an oral dose is unclear. Non-absorbed arabinogalactan is fermented by bacteria in the gastrointestinal tract (2), (3). Larch arabinogalactans are approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR172.610).This ingredient can be found in the following products:
References
• Advanced Ambrotose® capsules
• Advanced Ambrotose® powder
• AmbroStart® drink mix
• Ambrotose® Complex capsules
• Ambrotose® Complex powder
• CardioBALANCE® capsules
• Catalyst™ caplets
• EM•PACT®
• GlycoBears® tablets
• Manna-C™ capsules
• MannaCLEANSE™ caplets
• Optimal Support Packets
• Phyt-Aloe® capsules or powder
• PLUS™ caplets
• SPORT™ capsules
References
1. Cui SW. Polysaccharide Gums from Agricultural Products: Processing, Structures & Functionality. Lancaster, Pa.: Technomic Publishing Co., Inc., 2001.
2. Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.
3. Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern.Med Rev 1999;4:96-103.
Last updated March, 2009
Print This Ingredient- Beta-1,3-glucans (from curdlan)
Beta-1,3-glucans (from curdlan)
Beta-1,3-glucans are large polysaccharides that can be derived from the cell walls of algae, bacteria, fungi, yeast and plants. They are considered a form of soluble fiber that are indigestible by human intestinal enzymes (1).
Curdlan is a specific beta-1,3-glucan derived from the nonpathogenic bacterium, Alcaligenes faecalis. It is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) (2).This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.
Last updated March, 2009
Print This Ingredient- Bifidobacterium bifidum
Bifidobacterium bifidum
Bifidobacterium bifidum is a strain of lactic acid-producing bacteria normally found in the human intestine, more so in breast-fed infants than in adults. Bifidobacterium bifidum is considered a probiotic, beneficial bacteria that help maintain the health of the intestinal tract and aid in digestion. Probiotics also assist in nutrient absorption and help control the amount of harmful bacteria in the gut. Probiotics come from food sources, such as yogurt, but they can also be consumed as dietary supplements. Orally, Bifidobacterium bifidum seems to be well-tolerated by most people. No adverse effects from Bifidobacteria ingestion have been reported (1).
This ingredient can be found in the following products:
References
• GI-PRO® capsules
• MannaCLEANSE™ caplets
References
1. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
Last updated March, 2009
Print This Ingredient- Black currant fiber
Black currant fiber
Black currant fiber. The black currant shrub, Ribes nigrum, is native to areas in Europe and Asia. The black currant fruit, seed, bark and leaves are all used for dietary purposes (1). Black currant seeds contain high molecular weight polysaccharides and are a source of dietary fiber (2), (3).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Lengsfeld C, Deters A, Faller G, Hensel A. High molecular weight polysaccharides from black currant seeds inhibit adhesion of Helicobacter pylori to human gastric mucosa. Planta Med 2004;70:620-6.3. Tahvonen R, Hietanen A, Sankelo T, Korteniemi V, Laakso P, Kallio H. Black currant seeds as a nutrient source in breakfast cereals produced by extrusion cooking. Z Lebensm Unters Forsch A 1998;206:360-3.Last updated March, 2009
Print This Ingredient- Borage oil (seed)
Borage oil (seed)
Borage oil is derived from the seeds of the borage plant, Borago officinalis, an herb grown in the Middle East and the Mediterranean region. Borage oil is a rich source of the long-chain polyunsaturated fatty acid, gamma-linolenic acid (GLA), to which many of the health benefits of borage oil are attributed (1). Borage oil is likely safe when used orally and appropriately (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.
2. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.Last updated March, 2009
Print This Ingredient- Carrageenan
Carrageenan
Carrageenan is a sulfated polysaccharide extracted from species of red algae, including Gigartina skottsbergii, Chondrus crispus and Eucheuma cottonii. The solubility and gelling capability of carrageenans differ depending on the type of red algae used. Carrageenan has been used for hundreds of years as a food additive. In foods, it acts as a thickener and stabilizer (1). Carrageenan is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• GlycoSlim® chocolate meal replacement
• GlycoSlim® vanilla meal replacement
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Cellulase
Cellulase
Cellulase is an enzyme produced by fungi, bacteria and other microscopic organisms. Production of cellulase by intestinal bacteria helps with the digestion of plant cellulose and other beta-glucans, which are indigestible by human enzymes (1). Cellulase derived from widely utilized fungi, such as Aspergillus niger and Trichoderma longibrachiatum, is approved for use as a food enzyme by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• GI-ZYME® capsules
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Fennel (seed)
Fennel (seed)
Fennel, Foeniculum vulgare, is an herb native to the Mediterranean region. For centuries, fennel seeds have been a valued herb in Europe and China. Today, fennel is used as a flavor component in beverages, candy, baked goods and meat products. Fennel seed is a rich source of beta-carotene and vitamin C, and also contains significant amounts of calcium, magnesium and iron (1). Fennel is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a natural flavoring (21CFR182.10).
This ingredient can be found in the following products:
References
• GI-ZYME® capsules
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
Last updated March, 2009
Print This Ingredient- Fenugreek (seed)
Fenugreek (seed)
Fenugreek, Trigonella foenum-graecum, is an herb native to areas of Asia and Europe. It has a long history of use in traditional Indian and Chinese cultures. Fenugreek is commonly consumed as an ingredient in curry and many spice blends. Fenugreek seeds are also a source of dietary fiber (1). Fenugreek is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a spice or natural seasoning (21CFR182.10).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
Last updated March, 2009
Print This Ingredient- Flax (seed)
Flax (seed)
Flax (seed). Flax seeds are the seeds of the common flax, or linseed plant, Linum usitatissimum. They contain high levels of lignans, polyphenolic compounds that have been shown to be beneficial to human health. Flax seeds also contain a significant amount of the essential fatty acid, alpha-linolenic acid (ALA), a biological precursor to omega-3 fatty acids such as eicosapentanoic acid (EPA) (1). Flax seed appears to be well-tolerated, and there is long-standing historical use of flax seed products in dietary supplements (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.
2. Natural Standard Database. www.naturalstandard.com. 2009.Last updated March, 2009
Print This Ingredient- Ghatti gum
Ghatti gum
Ghatti gum, a mixture of complex polysaccharides, comes from the bark of Anogeissus latifolia, a large tree native to India and Sri Lanka. Ghatti gum is used in supplements, foods, drugs and cosmetics. It contains as much as 80% soluble dietary fiber (1). Gum ghatti is also used to aid in mixing skin care product ingredients.
Most gums are believed to be largely degraded in the colon (2). Test tube studies have demonstrated the fermentation of ghatti gum by the beneficial human bacteria species Bifidobacterium (3), (4). Ghatti gum is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is permitted for use as a food (21CFR184.1333).This ingredient can be found in the following products:
References
• Advanced Ambrotose® capsules
• Advanced Ambrotose® powder
• AmbroStart® drink mix
• Ambrotose AO® capsules
• Ambrotose® Complex capsules
• Ambrotose® Complex powder
• CardioBALANCE® capsules
• Catalyst™ caplets
• EM•PACT®
• Emprizone® gel
• FIRM with Ambrotose® cream
• GlycoBears® tablets
• Manna-C™ capsules
• MannaCLEANSE™ caplets
• Optimal Support Packets
• Phyt-Aloe® capsules or powder
• PLUS™ caplets
• SPORT™ capsules
References
1. Glicksman M. Gum Ghatti (Indian gum). In: Glicksman M, ed. Food Hydrocolloids. Boca Raton: CRC Press 1983:31-7.
2. Hill MJ. Bacterial fermentation of complex carbohydrate in the human colon. Eur J Cancer Prev 1995;4:353-8.
3. Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.
4. Salyers AA, West SE, Vercellotti JR, Wilkins TD. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl Environ Microbiol 1977;34:529-33.
Last updated March, 2009
Print This Ingredient- Ginger (root)
Ginger (root)
Ginger, Zingiber officinale, is an herb grown in a number of Asian, African and Caribbean countries. The roots and underground stems have long been used in traditional Chinese, Indian and Japanese cultures. Ginger is widely used as a food spice, especially in Oriental cooking. Dried powdered root is also used in herbal teas and supplements (1). Ginger is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a spice or natural seasoning (21CFR182.10).
This ingredient can be found in the following products:
References
• Catalyst™ caplets
• GI-ZYME® capsules
• GlycoBears® tablets
• MannaCLEANSE™ caplets
References
1. Leung A, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. New York, NY: John Wiley, 1996.
Last updated March, 2009
Print This Ingredient- Glucomannan
Glucomannan
Glucomannan is a polysaccharide derived from the tuber of the konjac plant, Amorphophallus konjac. It is used as a thickening agent in foods and is marketed in the United States as a dietary supplement. Glucomannan is considered a soluble dietary fiber that is indigestible by human intestinal enzymes. It can be degraded by intestinal bacteria into short chain fatty acids, such as propionic and butyric acids (1). Glucomannan is likely safe when used orally as food (2).
This ingredient can be found in the following products:
References
• FiberSlim™ capsules
• MannaCLEANSE™ caplets
References
1. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.
2. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.Last updated March, 2009
Print This Ingredient- Gum tragacanth
Gum tragacanth
Gum tragacanth comes from the stems and branches of the flowering plant Astragalus gummifer. The raw gum is made up of a mixture of two polysaccharides. Gum tragacanth has been approved for use in pharmaceuticals in the U.S. since 1820 and in foods since 1925 (1).
Most gums are believed to be largely degraded in the colon (2). Test tube studies have demonstrated that gum tragacanth can be digested by a number of bacteria that inhabit the human colon, including the beneficial Bifidobacterium species (3), (4). Gum tragacanth is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is commonly added to foods (21CFR184.1351).This ingredient can be found in the following products:
References
• Advanced Ambrotose® capsules
• Advanced Ambrotose® powder
• AmbroStart® drink mix
• Ambrotose AO® capsules
• Ambrotose® Complex capsules
• CardioBALANCE® capsules
• Catalyst™ caplets
• EM•PACT®
• GlycoBears® tablets
• MannaBears™ supplement
• Manna-C™ capsules
• MannaCLEANSE™ caplets
• Optimal Support Packets
• Phyt-Aloe® capsules or powder
• PLUS™ caplets
• SPORT™ capsules
References
1. Anderson DM. Evidence for the safety of gum tragacanth (Asiatic Astragalus spp.) and modern criteria for the evaluation of food additives. Food Addit Contam 1989;6:1-12.
2. Hill MJ. Bacterial fermentation of complex carbohydrate in the human colon. Eur J Cancer Prev 1995;4:353-8.
3. Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.
4. Salyers AA, West SE, Vercellotti JR, Wilkins TD. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl Environ Microbiol 1977;34:529-33.
Last updated March, 2009
Print This Ingredient- Inulin-oligosaccharide complex (from dried juice Dahlia variabilis tuber and chicory root)
Inulin-oligosaccharide complex (from dried juice Dahlia variabilis tuber and chicory root)
Inulin-oligosaccharide complex (from dried juice Dahlia variabilis tuber and chicory root). Inulin is a fructose-rich oligosaccharide that occurs naturally in plants, including a number of fruits and vegetables such as onions, leeks, garlic, bananas, asparagus and artichokes. Inulin is commonly added to foods due to its sweet taste and texture. Intake in the U.S. ranges from 1 to 4 grams daily. Inulin is considered a form of soluble fiber that is sometimes seen as a prebiotic, a non-digestible food ingredient that promotes the growth and/or activity of beneficial bacteria in the colon. Inulin-type prebiotics also include fructooligosaccharides and oligofructose (1). The U.S. Food and Drug Administration (FDA) has been notified that industry considers inulin to be generally recognized as safe (GRAS) for use in foods and has not objected to their use for this purpose (GRN No. 000118).
Dahlia plants, such as Dahlia variabilis, are native to Mexico and Central America. They are widely cultivated for their various colorful flower heads. The fructose-containing oligosaccharide, inulin, can be obtained from the dried juice of dahlia tubers (2).
Chicory, Cichorium intybus, is a plant native to Europe and areas of Asia. It was cultivated by ancient Egyptians, and is now consumed as a vegetable in salads in Europe and the United States. Fructans, such as inulin and oligofructose, are extracted from chicory roots (3).This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.
2. Kaur N, Gupta AK. Applications of inulin and oligofructose in health and nutrition. J Biosci. 2002;27:703-14.3. Natural Standard Database. www.naturalstandard.com. 2009.Last updated March, 2009
Print This Ingredient- Lactase
Lactase
Lactase is an enzyme that breaks down lactose, a disaccharide found in milk, into the monosaccharides glucose and galactose. In humans, lactase is located on the membranes of epithelial cells lining the small intestine. Lactose intolerance is caused by the absence or deficiency of this enzyme in the intestinal system (1). Lactase derived from certain strains of yeast is approved for use as a food enzyme by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• GI-ZYME® capsules
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Lactobacillus acidophilus
Lactobacillus acidophilus
Lactobacillus acidophilus is a strain of lactic acid-producing bacteria that is naturally found in the human gastrointestinal tract. It is commonly found in fermented milk products, such as yogurt, and can also be consumed as a dietary supplement. Lactobacillus acidophilus is considered a probiotic, beneficial bacteria that help maintain the health of the intestinal tract and aid in digestion. Probiotics also assist in nutrient absorption and help control the amount of harmful bacteria in the gut. Orally, Lactobacillus species are usually well-tolerated, the most common side effect being a mild case of flatulence that tends to subside as consumption continues (1).
This ingredient can be found in the following products:
References
• GI-PRO® capsules
• MannaCLEANSE™ caplets
References
1. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
Last updated March, 2009
Print This Ingredient- Lactobacillus casei
Lactobacillus casei
Lactobacillus casei is a strain of lactic acid-producing bacteria normally found in the human intestine. It is considered a type of probiotic, beneficial bacteria that help maintain the health of the intestinal tract and aid in digestion. Probiotics also assist in nutrient absorption and help control the amount of harmful bacteria in the gut. Probiotics come from food sources, such as yogurt, but they can also be consumed as dietary supplements. Orally, Lactobacillus species are usually well-tolerated, the most common side effect being a mild case of flatulence that tends to subside as consumption continues (1).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
Last updated March, 2009
Print This Ingredient- Lactobacillus plantarum
Lactobacillus plantarum
Lactobacillus plantarum is a strain of lactic acid-producing bacteria that is naturally found in the human gastrointestinal tract. It is commonly found in fermented food products and can be consumed as a probiotic dietary supplement. Probiotics are beneficial bacteria that help maintain the health of the intestinal tract and aid in digestion. They also assist in nutrient absorption and help control the amount of harmful bacteria in the gut. Orally, Lactobacillus species are usually well-tolerated, the most common side effect being a mild case of flatulence that tends to subside as consumption continues (1).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
Last updated March, 2009
Print This Ingredient- Lactobacillus sporogenes
Lactobacillus sporogenes
Lactobacillus sporogenes, also referred to as Bacillus coagulans, is a strain of lactic acid-producing bacteria used as a probiotic in foods and dietary supplements. Probiotics are beneficial bacteria that help maintain the health of the intestinal tract and aid in digestion. They also assist in nutrient absorption and help control the amount of harmful bacteria in the gut. Orally, Lactobacillus species are usually well-tolerated, the most common side effect being a mild case of flatulence that tends to subside as consumption continues (1).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
Last updated March, 2009
Print This Ingredient- Lipase
Lipase
Lipase is an enzyme that digests fat-soluble molecules called lipids. It is found in many plants, milk, dairy products, bacteria, molds and animal tissues. In the human digestive system, lipase is made by the pancreas and secreted into the intestines to help break down dietary fats (1). Lipase derived from animal tissue and certain nontoxic and nonpathogenic fungi is approved for use as a food enzyme by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• GI-PRO® capsules
• GI-ZYME® capsules
• MannaCLEANSE™ caplets
References
1. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.
Last updated March, 2009
Print This Ingredient- Oat fiber
Oat fiber
Oat fiber. Oats contain a large amount of soluble fiber, consisting of polysaccharides called beta-glucans. Consumption of oat beta-glucans has beneficial effects on human health (1). They are approved for use as a source of dietary fiber by the U.S. Food and Drug Administration (FDA) (21CFR101.81).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.
Last updated March, 2009
Print This Ingredient- Orange (flower)
Orange (flower)
Orange (flower). The bitter orange tree, Citrus aurantium, is a flowering, citrus fruit-bearing tree native to tropical Asia. Over the centuries, bitter orange has been highly valued as a food and for its health benefits. The bitter orange peel, flowers and leaves contain flavonoids that have antioxidant activities (1). The flowers of Citrus aurantium are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as food additives (21CFR182.20) (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Peppermint (aerial part)
Peppermint (aerial part)
Peppermint, Mentha piperita, is an herb grown throughout much of Europe and North America. Peppermint (aerial parts and oil) has a long history of traditional use and is a common flavoring agent. It contains menthol, carotene, tocopherols, flavonoids and other polyphenols (1). Peppermint is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a natural flavoring (21CFR182.10).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
Last updated March, 2009
Print This Ingredient- Protease
Protease
Proteases are protein-digesting enzymes. While they occur naturally in all organisms, proteases in supplements are typically obtained from safe, non-pathogenic fungi. Orally administered protein-digesting enzymes can be detected in human blood, at least to some extent, in their intact, biologically active form (1).
This ingredient can be found in the following products:
References
• BounceBack® capsules
• MannaCLEANSE™ caplets
References
1. Kolac C, Streichhan P, Lehr C-M. Oral bioavailability of proteolytic enzymes. Eur J Pharmacol Biopharm 1996;42:222-32.
Last updated March, 2009
Print This Ingredient- Psyllium (seed husk)
Psyllium (seed husk)
Psyllium (seed husk) is a mixture of polysaccharides derived from the husks of the seeds of Plantago plant species. It has a high level of soluble dietary fiber. Psyllium is used in processed foods, such as cereals, and in various dietary supplement formulations to increase fiber intake. It passes through the gastrointestinal tract largely unchanged (1). Psyllium seed husk is approved for use as a source of dietary fiber by the U.S. Food and Drug Administration (FDA) (21CFR101.81) (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Rice bran
Rice bran
Rice bran is made from the bran layer, underneath the hull layer, of rice, Oryza sativa. Rice bran is high in dietary fiber, and is an excellent source of protein, vitamin E, thiamin, niacin, vitamin B6, pantothenic acid and a number of minerals, such as iron and magnesium. It is also a good source of folate and riboflavin (1). Rice bran also contains beta-sitosterol and other phytosterols, along with the essential omega-3 fatty acid alpha-linolenic acid (ALA) (2).
This ingredient can be found in the following products:
References
• Catalyst™ caplets
• MannaCLEANSE™ caplets
References
1. United States Department of Agriculture. USDA National Nutrient Database for Standard Reference, Release 21. http://www.ars.usda.gov/main/site_main.htm?modecode=12-35-45-00. 2008.
2. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.Last updated March, 2009
Print This Ingredient- Rosemary (aerial part)
Rosemary (aerial part)
Rosemary, Rosmarinus officinalis, is a small evergreen shrub grown in many parts of the world. The fresh and dried leaves are used as flavoring agents and food preservatives. Rosemary has been used for centuries as a valued herb. It contains a number of phytochemicals that demonstrate antioxidant activity, including caffeic, carnosic and rosmarinic acids (1). Rosemary is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a spice or natural seasoning (21CFR182.10).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Natural Standard Database. www.naturalstandard.com. 2009.
Last updated March, 2009
Print This Ingredient- Sodium caprylate
Sodium caprylate
Sodium caprylate is the sodium salt of caprylic acid, a medium chain fatty acid. Medium chain fatty acids are found in medium chain triglycerides, which are sometimes used as nutritional agents (1). Sodium caprylate is typically used in foods as a binder, to aid in the mixing of ingredients and to prevent caking. Sodium caprylate is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) (21CFR172.863) (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Soy lecithin
Soy lecithin
Soy lecithin is a combination of naturally occurring phospholipids extracted during the processing of soybean oil. It consists of three types of phospholipids- phosphatidylcholine, phosphatidylethanolamine and phosphotidylinositol. Soy lecithin is used commercially in substances as a natural way to stabilize liquid mixtures. Lecithin is approved by the U.S. Food and Drug Administration (FDA) for human consumption with the status generally recognized as safe (GRAS) (21CFR184.1400).
This ingredient can be found in the following products:
References
• AmbroStart® drink mix
• EM•PACT®
• MannaCLEANSE™ caplets
• Optimal Support Packets
• OsoLean® powder
• PhytoMatrix® caplets
Formulation Ingredients
- Croscarmellose sodium
Croscarmellose sodium
Croscarmellose sodium, the sodium salt of a cellulose, is added to capsules, tablets and granules to help them disintegrate following ingestion. Croscarmellose sodium is generally regarded as an essentially nontoxic material. Consumption of large quantities may have a laxative effect, although the quantities used in capsules or tablets are unlikely to cause this problem (1).
This ingredient can be found in the following products:
References
• Catalyst™ caplets
• MannaCLEANSE™ caplets
• Optimal Support Packets
• PhytoMatrix® caplets
• PLUS™ caplets
References
1. Handbook of Pharmaceutical Excipients. Gurnee, IL: Pharmaceutical Press, 2006.
Last updated March, 2009
Print This Ingredient- Dicalcium phosphate dihydrate
Dicalcium phosphate dihydrate
Dicalcium phosphate dihydrate (calcium phosphate, dibasic) is a white, odorless, tasteless powder used both as an excipient and as a source of calcium and phosphorous in dietary supplements. It is widely used in the nutritional and health food sectors (1). Calcium phosphate, dibasic is an approved food additive by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Hydroxypropyl cellulose
Hydroxypropyl cellulose
Hydroxypropyl cellulose (HPC) is a derivative of cellulose that is water-soluble. HPC is used in food products as a thickener and to stabilize oil-in-water mixtures. It is also used in oral formulations (i.e. capsules and tablets) as a binder and to assist in disintegration (1). Hydroxypropyl cellulose is an approved food additive by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Hydroxypropyl methylcellulose
Hydroxypropyl methylcellulose
Hydroxypropyl methylcellulose (HPMC), also known as hypromellose, is a derivative of cellulose. In oral products, HPMC is primarily used as a binder and for encapsulation as an alternative to animal-derived gelatin. In foods, it is used as a thickener and to stabilize oil-in-water mixtures (1). Hydroxypropyl methylcellulose is an approved food additive by the U.S. Food and Drug Administration (FDA) (2).
This ingredient can be found in the following products:
References
• MannaCLEANSE™ caplets
References
1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.
2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.Last updated March, 2009
Print This Ingredient- Magnesium stearate
Magnesium stearate
Magnesium stearate, a salt of stearic acid, is widely used in cosmetics, foods, and capsules as a lubricating agent. In dietary supplements it may contain a mixture of magnesium salts of different fatty acids.
Magnesium stearate is approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR184.1440) and is generally regarded as being nontoxic following oral administration. Oral consumption of large quantities may produce a laxative effect or cause mucosal irritation (1).This ingredient can be found in the following products:
References
• CardioBALANCE® capsules
• Catalyst™ caplets
• FiberSlim™ capsules
• GlycoBears® tablets
• MannaCLEANSE™ caplets
• Optimal Support Packets
• PhytoMatrix® caplets
• PLUS™ caplets
• SPORT™ capsules
References
1. Handbook of Pharmaceutical Excipients. Gurnee, IL: Pharmaceutical Press, 2006.
Last updated March, 2009
Print This Ingredient- Microcrystalline cellulose
Microcrystalline cellulose
Microcrystalline cellulose (MC) is a purified plant fiber that is widely used in food products and in dietary supplement tablets to: 1) bind ingredients together, or 2) help the tablet disintegrate properly.
Following ingestion, MC is not absorbed by the human body. Because it is not absorbed, it has little potential for toxicity. Consumption of large quantities of cellulose may have a laxative effect, but this is unlikely to be a problem for individuals consuming the small amounts included in dietary supplement tablets (1).This ingredient can be found in the following products:
References
• BounceBack® capsules
• Catalyst™ caplets
• MannaCLEANSE™ caplets
• Optimal Support Packets
• PhytoMatrix® caplets
• PLUS™ caplets
References
1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.
Last updated March, 2009
Print This Ingredient- Natural flavor(s)
Natural flavor(s)
Natural flavors are oils or extracts containing the flavoring constituents derived from a spice, fruit or fruit juice, vegetable or vegetable juice, edible yeast, herb, bark, bud, root, leaf or similar plant material, meat, seafood, poultry, eggs or dairy products, whose significant function in food is flavoring rather than nutritional (21CFR501.22).
This ingredient can be found in the following products:
References
• AmbroStart® drink mix
• EM•PACT®
• GlycoBears® tablets
• GlycoSlim® chocolate meal replacement
• GlycoSlim® vanilla meal replacement
• ImmunoSTART® tablets
• MannaBears™ supplement
• MannaCLEANSE™ caplets
- Silicon dioxide
Silicon dioxide
Silicon dioxide, also known as silica, is added to capsule and tablet formulations to reduce clumping (1). Silica is found in many foods, particularly whole grains (oats and barley), sugar beets, sugar cane, soybeans, turnips, green beans (2). The average intake of silica in adults is 14-21 mg/day (3). The bioavailability of silicate additives is low (4). Silica that occurs in food and water has not been shown to cause any adverse effects (3).
This ingredient can be found in the following products:
References
• Accelerator 3™ capsules
• AmbroStart® drink mix
• Ambrotose® Complex capsules
• BounceBack® capsules
• Catalyst™ caplets
• EM•PACT®
• FiberSlim™ capsules
• GlycoBears® tablets
• GlycoSlim® chocolate meal replacement
• GlycoSlim® vanilla meal replacement
• ImmunoSTART® tablets
• MannaCLEANSE™ caplets
• Optimal Support Packets
• PhytoMatrix® caplets
• PLUS™ caplets
• SPORT™ capsules
References
1. The Merck Index. Whitehouse Station, NJ: Merck & Co., 2006.
2. Nutritional Biochemistry and Metabolism. New York, New York: Elsevier, 1991.
3. Natural Medicines: Comprehensive Database. Stockton, CA: Therapeutic Research Faculty, 2000.
4. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.
Last updated March, 2009
Print This Ingredient- Stearic acid
Stearic acid
Stearic acid is a naturally occurring fatty acid that is found in animal and vegetable fats. In dietary supplements, it is typically a combination of stearic and palmitic acids. Stearic acid is used as a lubricantin capsules and tablets and is also used widely in cosmetics and food products (1). It is used in topical formulations to assist in mixing ingredients and to stabilize oil-in-water mixtures (2).
Stearic acid is approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR184.1090) and is generally regarded as a nontoxic and nonirritating material (1). It is also included in the U.S. FDA Inactive Ingredients Guide as safe to use in the amounts present in our products (3).This ingredient can be found in the following products:
References
• Ambrotose® Complex capsules
• Catalyst™ caplets
• FIRM with Ambrotose® cream
• GlycoBears® tablets
• MannaCLEANSE™ caplets
• Optimal Support Packets
• Phyt-Aloe® capsules or powder
• PLUS™ caplets
References
1. Handbook of Pharmaceutical Excipients. Gurnee, IL: Pharmaceutical Press, 2006.
2. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.
3. FDA Inactive Ingredients Guide. http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm. 2007.
Last updated March, 2009
Print This Ingredient
* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.