Mannatech Science

Emprizone

Emprizone® gel
Soothing, hydrating skin care

Mannatech Skin Care Product Safety And Efficacy Testing


    

Ingredients

OpenAllantoin

Allantoin

Allantoin is an organic compound used in cosmetics and personal care products as a skin conditioning agent (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), allantoin is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •   Body Lotion
   •   Day Moisturizer
   •   Emprizone® gel
   •   Multiphase Serum
 

References

References

1.  International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated March, 2009

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OpenAloe barbadensis leaf extract

Aloe barbadensis leaf extract

Aloe barbadensis leaf extract is the powder obtained from the freeze-dried gel of the leaves of the aloe vera plant, Aloe barbadensis.

For centuries, the plant aloe vera has been used by cultures for its beneficial effects on human health (1). Today aloe vera gel continues to be used in supplements, foods, beverages, and cosmetics. Aloe leaves consist of two major parts, the outer leaf epidermis and the inner leaf gel, which are very different in their chemical composition and properties. Aloe gel is obtained from the inner portion of the leaves. Aloe gel is rich in nutrients and contains an abundant supply of glycoproteins and mono-, oligo- and polysaccharides. Monosaccharide constituents include glucose, mannose, galacturonic acid, glucuronic acid, galactose, arabinose, fucose, glucosamine, fructose, rhamnose and xylose (2).

Much of the health benefits observed by the use of aloe vera gel may be attributed to its high molecular weight polysaccharides. Before a process was developed to stabilize aloe vera gel or extracts, fresh preparations were regarded as being required for any therapeutic efficacy (3). It has now been shown that careful drying of aloe vera gel can retain the polysaccharide content important for producing many of its health benefits (4).

 Today aloe vera gel continues to be used in cosmetics and personal care products as a skin conditioning agent, which acts both to lubricate the skin surface and to increase water content of the top layers of the skin by drawing moisture from the surrounding air (5). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), Aloe barbadensis leaf extractis safe to use in the amounts present in our products (6).

 

 This ingredient can be found in the following products:
    •  Emprizone® gel
    •  FIRM with Ambrotose® cream
 

References

References

1.  The Merck Index. Whitehouse Station, NJ: Merck & Co., Inc., 1996.

2.  Duncan, C., Ramberg, J., and Sinnott, R. Striking differences in Aloe vera gel carbohydrate composition, molecular weight and particle size distributions following processing will not be addressed by dietary supplement GMPs. Poster Presentation at the 5th Annual Natural Supplements Conference, January 17-20, 2008, Scripps Center for Integrative Medicine, San Diego, California.

3.  Gjerstad G, Riner TD. Current status of aloe as a cure-all. Am J Pharm Sci Support Public Health 1968;140:58-64.

4.  Ni Y, Turner D, Yates KM, Tizard I. Isolation and characterization of structural components of Aloe vera L. leaf pulp. Int J Immunopharmacol. 2004;4:1745-55.

5.  International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

6.  Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table.  http://www.cir-safety.org/staff_files/PublicationsListDec2009.pdf . 2009.

Last updated June, 2012

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OpenAminomethyl propanol

Aminomethyl propanol

Aminomethyl propanol is a chemical compound used to adjust the pH (acidity or alkalinity) of skin care products (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), aminomethyl propanol is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
 

References

References

1.  International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated March, 2009

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OpenAstragalus gummifer gum

Astragalus gummifer gum

Astragalus gummifer gum comes from the stems and branches of the flowering plant Astragalus gummifer. The raw gum is made up of a mixture of two polysaccharides. Monosaccharide constituents include galactose, arabinose, xylose, fucose, rhamnose, and galacturonic acid. It is used to increase the thickness of skin care products, for fragrance and to stabilize oil-in-water mixtures. According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), Astragalus gummifer gum is safe to use in the amounts present in our products

This ingredient can be found in the following products:
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
 

References

References

1. Anderson DM, Howlett JF, McNab CG. The amino acid composition of the proteinaceous component of gum tragacanth. Food Addit Contam 1985;2:231-5.

2. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

3. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/PublicationsListDec2009.pdf . 2009.

Last updated January, 2011

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OpenBenzethonium chloride

Benzethonium chloride

Benzethonium chloride is an organic compound that aids in the mixing of skin care products. It also has antimicrobial activity that protects cosmetics and personal care products from spoilage (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), benzethonium chloride is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
 

References

References

1.  International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated March, 2009

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OpenCarbomer

Carbomer

Carbomer is the name given to a group of synthetically derived chemical compounds that are used in skin care products to assist in the mixing of ingredients (1). Various carbomers are included in the U.S. Food and Drug Administration (FDA) Inactive Ingredients Guide as safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. FDA Inactive Ingredients Guide. http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm. 2007.

Last updated March, 2009

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OpenDisodium EDTA

Disodium EDTA

Disodium EDTA, a salt of the chelating agent ethylenediaminetetraacetic acid (EDTA), binds to and inactivates metal ions to prevent the deterioration of cosmetics and personal care products (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), disodium EDTA is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Body Lotion
   •  Day Moisturizer
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
   •  Multiphase Serum
   •  Night Repair Crème
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated September, 2010

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OpenGalactoarabinan

Galactoarabinan

Galactoarabinan, or arabinogalactan,is a polysaccharide extracted for commercial uses from the bark of the Eastern and Western Larch trees, Larix larcinia and Larix occidentalis. Monosaccharide constituents include galactose, arabinose, glucose and mannose (1). It is used in skin care products as a fragrance and as an ingredient that dries to form a thin coating on the skin (2).

This ingredient can be found in the following products:
   •  Body Lotion
   •  Day Moisturizer
   •  Emprizone® gel
   •  Exfoliating Facial Cleanser
   •  FIRM with Ambrotose® cream
   •  Multiphase Serum
   •  Night Repair Crème
 

References

References

 1.    Luta G, Duncan C, Sinnott R. Chemical characterization of polysaccharide-rich ingredients from Aloe vera, Larix laricina and Larix occidentalis, and Undaria pinnatifida. Presented at the Scripps Center for Integrative Medicine's 6th Annual Natural Supplements Conference, San Diego, California.January 22-25, 2009. 2009. 

 2.     International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

Last updated January, 2011

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OpenGhatti gum

Ghatti gum

 

Ghatti gum, a mixture of complex polysaccharides, comes from the bark of Anogeissus latifolia, a large tree native to India and Sri Lanka. Monosaccharide constituents include arabinose, galactose, mannose, xylose and glucuronic acid. Ghatti gum is used in supplements, foods, drugs and cosmetics. It contains as much as 80% soluble dietary fiber (1).
 
Most gums are believed to be largely degraded in the colon (2). Test tube studies have demonstrated the fermentation of ghatti gum by the beneficial human bacteria species Bifidobacterium (3),(4). Ghatti gum is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is permitted for use as a food (21CFR184.1333).

 This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  AmbroStart® drink mix
   •  Ambrotose AO® capsules
   •  Ambrotose® Complex capsules
   •  Ambrotose® Complex powder
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  EM•PACT®
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
   •  Manna-C™ capsules
   •  MannaCLEANSE™ caplets
   •  Optimal Support Packets
   •  Phyt-Aloe® capsules or powder
   •  PLUS™ caplets
   •  SPORT™ capsules
 

References

References

1. Glicksman M. Gum Ghatti (Indian gum). In: Glicksman M, ed. Food Hydrocolloids. Boca Raton: CRC Press 1983:31-7.

2. Hill MJ. Bacterial fermentation of complex carbohydrate in the human colon. Eur J Cancer Prev 1995;4:353-8.

3. Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.

4. Salyers AA, West SE, Vercellotti JR, Wilkins TD. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl Environ Microbiol 1977;34:529-33.

Last updated March, 2013

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OpenGlycereth-26

Glycereth-26

Glycereth-26 is a chemical compound derived from glycerin. It is used to decrease the thickness of skin care products and as a skin conditioning agent that increases water content of the top layers of the skin by drawing moisture from the surrounding air (1).

This ingredient can be found in the following products:
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

Last updated March, 2009

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OpenGlycerin

Glycerin

Glycerin is a chemical compound used in skin care products and cosmetics as a humectant, that is, a skin conditioning agent that increases water content of the top layers of the skin by drawing moisture from the surrounding air. Glycerin also acts as a lubricant on the skin surface, which gives the skin a soft and smooth appearance (1). It is included in the U.S. Food and Drug Administration (FDA) Inactive Ingredients Guide as safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Day Moisturizer
   •  Emprizone® gel
   •  Exfoliating Facial Cleanser
   •  FIRM with Ambrotose® cream
   •  Multiphase Serum
   •  Night Repair Crème
 

References

References

1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.

2. FDA Inactive Ingredients Guide. http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm. 2007.

Last updated September, 2010

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OpenGlyceryl polyacrylate

Glyceryl polyacrylate

Glyceryl polyacrylate is a chemical compound derived from glycerin. It is used in cosmetics and personal care products as an ingredient that dries to form a thin coating on the skin (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), glyceryl polyacrylate is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated March, 2009

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OpenGum tragacanth

Gum tragacanth

Gum tragacanth comes from the stems and branches of the flowering plant Astragalus gummifer. The raw gum is made up of a mixture of two polysaccharides. Monosaccharide constituents include galactose, arabinose, xylose, fucose, rhamnose, and galacturonic acid (1). Gum tragacanth has been approved for use in pharmaceuticals in the U.S. since 1820 and in foods since 1925 (2). Most gums are believed to be largely degraded in the colon (3). Test tube studies have demonstrated that gum tragacanth can be digested by a number of bacteria that inhabit the human colon, including the beneficial Bifidobacteria species (4),(5). Gum tragacanth is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is commonly added to foods (21CFR184.1351).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  AmbroStart® drink mix
   •  Ambrotose AO® capsules
   •  Ambrotose® Complex capsules
   •  Ambrotose® Complex powder
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  EM•PACT®
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
   •  Manna-C™ capsules
   •  MannaCLEANSE™ caplets
   •  NutriVerus™ powder
   •  Optimal Support Packets
   •  Phyt-Aloe® capsules or powder
   •  PLUS™ caplets
   •  SPORT™ capsules
 

References

References

1. Anderson DM, Howlett JF, McNab CG. The amino acid composition of the proteinaceous component of gum tragacanth (Asiatic Astragalus spp.). Food Addit Contam 1985;2:231-5.

2.  Anderson DM. Evidence for the safety of gum tragacanth (Asiatic Astragalus spp.) and modern criteria for the evaluation of food additives. Food Addit Contam 1989;6:1-12.

3.  Hill MJ. Bacterial fermentation of complex carbohydrate in the human colon. Eur J Cancer Prev 1995;4:353-8.

4.  Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.

5.  Salyers AA, West SE, Vercellotti JR, Wilkins TD. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl Environ Microbiol 1977;34:529-33.

Last updated March, 2013

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OpenHexanediol (1,2-Hexanediol)

Hexanediol (1,2-Hexanediol)

1,2-Hexanediol is an organic alcohol used to aid in mixing of skin care products (1).

This ingredient can be found in the following products:
   •  FIRM with Ambrotose® cream
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

Last updated March, 2009

Print This Ingredient
OpenPolysorbate 80

Polysorbate 80

Polysorbate 80 is an organic compound used in skin care products as a fragrance and to aid in stabilizing oil-in-water mixtures (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), polysorbate 80 is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated March, 2009

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OpenRetinyl palmitate

Retinyl palmitate

Retinyl palmitate, or vitamin A palmitate, is an ester of retinol and palmitic acid. It is commonly used as a source of vitamin A in dietary supplements and fortified foods, such as milk. Retinyl palmitate is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a nutrient supplement in foods (21CFR184.1930) (1). It is also used as a skin conditioning agent in cosmetics and personal care products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
 

References

References

1. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

2. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

Last updated April, 2009

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OpenSalicylic acid

Salicylic acid

Salicylic acid is an organic compound that occurs naturally in the bark of the willow tree, Salix alba. It is used in skin care products as a fragrance and as a lubricant on the skin surface, which gives the skin a soft and smooth appearance (1). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), salicylic acid is safe to use in the amounts present in our products (2).

This ingredient can be found in the following products:
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated March, 2009

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OpenSodium hyaluronate

Sodium hyaluronate

Sodium hyaluronate is an organic compound used as a skin conditioning agent (1). It is generally regarded as a relatively nontoxic and nonirritant material (2).

This ingredient can be found in the following products:
   •  Body Lotion
   •  Day Moisturizer
   •  Emprizone® gel
   •  Multiphase Serum
   •  Night Repair Crème
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.

Last updated September, 2010

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OpenSorbitol

Sorbitol

Sorbitol is a sugar alcohol often used as a sweetener substitute in “sugar-free” foods. In cosmetics and personal care products, sorbitol is used as a skin conditioning agent that increases water content of the top layers of the skin by drawing moisture from the surrounding air (1). Sorbitol is included in the U.S. Food and Drug Administration (FDA) Inactive Ingredients Guide as safe to use in the amounts present in our products (2). It is also approved for use as a food additive by the U.S. FDA (3).

This ingredient can be found in the following product:
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

2. FDA Inactive Ingredients Guide. http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm. 2007.

3. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

Last updated March, 2013

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OpenTocopherol

Tocopherol

Tocopherols, along with tocotrienols, are organic compounds collectively known as vitamin E. Natural tocopherols exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (1). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (2).
     In cosmetics and personal care products, tocopherol is used as a skin conditioning agent that slows the loss of water from the skin by forming a barrier on the skin’s surface (3). According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), tocopherol is safe to use in the amounts present in our products (4).

This ingredient can be found in the following products:
   •  Body Lotion
   •  Day Moisturizer
   •  Emprizone® gel
   •  Multiphase Serum
   •  Night Repair Crème
 

References

References

1. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.

2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

3. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

4. Cosmetic Ingredient Review. Cosmetic Ingredients Reference Table. http://www.cir-safety.org/staff_files/ReferenceTable.pdf. 7-31-2008.

Last updated September, 2010

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OpenTocopheryl acetate

Tocopheryl acetate

Tocopheryl acetate is an organic compound used in cosmetics and personal care products as a skin-conditioning agent. It also has antioxidant activities (1).

This ingredient can be found in the following products:
   •  Body Lotion
   •  Emprizone® gel
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

Last updated September, 2010

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OpenWater (Aqua)

Water (Aqua)

This ingredient can be found in the following products:
   •  Body Lotion
   •  Day Moisturizer
   •  Emprizone® gel
   •  Exfoliating Facial Cleanser
   •  FIRM with Ambrotose® cream
   •  Multiphase Serum
   •  Night Repair Crème
 

References

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